The seeds of the indigenous plant caesalpinia sappan l. Pdf caesalpinia sappan an economic medicinal tree for the. Caesalpinia sappan is a medicinal tree which can give income within a short period of 78 years. Caesalpinia span heartwood is used in folklore in india.
Caesalpinia sappan cs is known to reduce inflammation and improve blood circulation. The seeds should be treated with diluted h 2 so 4 for six minutes. Sappan is considered a valuable astringent, alterative tonic, emmenagogue, blood purifier and anticoagulant. Pdf meiyanto2018 article caesalpinia sappan researchgate. Caesalpinia sappan grows wildly in mountainous regions and as an ornamental tree it is cultivated in yard and gardens because of its yellow coloured flowers. Caesalpinia sappan, a plant widely used in the traditional medicinal systems of india has been reported to possess antibacterial, antiinflammatory, antioxidant, anticancer and immunosuppressive activities.
Caesalpinia sappan, biancaea sappan, sappanwood, bukkum. Caesalpinia article about caesalpinia by the free dictionary. Caesalpinia a genus of plants of the family caesalpiniaceae. Evaluation of antioxidant and anthelmintic properties of. It is a small thorny tree, 69 m in height and 1525 cm in diameter. It strengthens the bones and teeth and is also used in boils and eruptions. Any variations in pre and post proving findings by comparing pre trial and post trial medical. Pdf brazilin from caesalpinia sappan wood as an antiacne agent. An innovative approach in developing sustained release matrix. Background rheumatoid arthritis ra is a systemic inflammatory disease of the synovium, cartilage, and bone. This study verifies the antioxidant and antitumor characteristics of brazilein in skin cancer cells and is the first time to elucidate the inhibition mechanism of adipocyte differentiation. Pharmacognostical evaluation of caesalpinia sappan heartwood. Pharmacognostic studies on sappan caesalpinia sappan. Caesalpinia sappan caesalpinia sappan, biancaea sappan x 69k jpg toptropicals.
Phytochemical screening and antimicrobial activity of. Twig dieback lasiodiplodia theobromaethis plant has many uses. The specific extraction temperature and extraction time were set as shown in fig. Germplasm resources information network grin, 2007 2011, database version 2011 acquired. Caesalpinia sappan is a kind of commonly used traditional chinese medicine, and it has. It is used as an ingredient in traditional foods and beverages 4. A decoction of the wood has shown antibiotic activity against staphylococcus, salmonella typhi, shigella flexneri, shigella dysenteriae and bacillus subtilis. Cs is distributed in southeast asia and its dried heartwood has been used as traditional ingredient of food or beverages and has a wide variety of medicinal properties. This study aimed to understand the antirheumatoid activity of brazilin that was isolated from ethyl acetate extract of c. Wo2007066928a1 use of the extract of caesalpinia sappan l. Provided by ars systematic botany and mycology laboratory.
How sappan wood is effective for various diseases is listed in repertory format. In thai folk medicine, it is used as an emmenagogue and strong astringent. It is still used for dyeing textiles, but only on a smaller. Caesalpinia sappan an economic medicinal tree for the tropics. The present work contributes for the standardization of this medicinal heat wood. An extract of caesalpinia sappan was found to be a potent agent for inactivating human sperm in vitro. Photograph of caesalpinia sappan plant with insight showing fruit, flower, wood and heartwood. Toxicological studies of caesalpinia sappan wood derived. Sappan wood herb uses, benefits, cures, side effects.
It is native to tropical america probably the west indies, but is now widely grown in tropical areas around the world for its long bloom of colorful. The drug is ascribed to the heartwood ofcaesalpinia sappan. The evaluations were conducted in mice with typeii collageninduced arthritis cia. Caesalpinia sappan wood su mu chinese herbs healing. Moreover, these plants are rich sources of certain. The tree is cultivated in the gardens for its large, ornamental panicals of yellow flowers.
The present invention relates to an extract of caesalpinia sappan l. In indonesia, its heartwood is traditionally used for skin care. Natural dyes taken from the barks of the tree caesalpinia sappan has been used in many consumer products. Caesalpinia is a genus of flowering plants in the legume family, fabaceae. Acero and others published termiticidal potential of sappan caesalpinia sappan seeds find, read and cite all the research you need on researchgate. Accordingly, a detailed pharmacognosy ofcaesalpinia sappan was carried out and eight market samples of sappan procured from various parts.
Four new phenolic compounds, caesalpiniaphenols ad 14, together with eight known compounds were isolated from caesalpinia sappan heartwood. Leguminosae is a traditional medicinal plant distributed in the asian peninsula including india, burma, vietnam, sri lanka, and china. An innovative approach in developing sustained release. The chemical structures were established mainly by nmr, ms, ecd, and moshers method.
The aim of this study is to evaluate the antidiabetic activity of ethanolic extract of caesalpinia sappan wood in albino wistar rat models invivo and inhibition of. Bioassayguided fractionation of a methanol extract of the seeds of caesalpinia sappan led to the isolation of 12 new cassanetype diterpenes, caesalsappanins al 112. Compounds 4, 5, and 7 showed weak inhibitory activity against the lpsinduced no production in macrophage raw264. Heartwood in various ages penpun wetwitayaklung a, thawatchai phaechamud b and sindhchai keokitichai c a department of pharmacognosy, faculty of pharmacy, silpakorn university, nakornpathom 73000, thailand. National germplasm resources laboratory, beltsville, maryland. Tumbuhan herbal kaya antioksidan ramdana sari dan suhartati 57 secang caesalpinia sappan l. Antiinflammatory and wound healing effects of caesalpinia.
Caesalpinia sappan is a small to mediumsized, shrubby tree, 48 m tall. It remained a major source of red dye up to the end of the 19 th century. Brazilein, a natural, biologically active compound from caesalpinia sappan l. Pdf termiticidal potential of sappan caesalpinia sappan. Cs is a plant of leguminosae family, commonly known as brazil or sappan wood. Caesalpinia sappan, a plant widely used in the traditional medicinal systems of india has been reported to possess antibacte rial, antiinflammatory, antioxidant. The aim of the study is to develop a galactomannanbased drug delivery system. Pdf termiticidal potential of sappan caesalpinia sappan seeds. Their structures were elucidated on the basis of nmr and hresims analysis, and the absolute configuration of compound 1 was determined by singlecrystal xray crystallography. Godofredo umali stuart, with botanical information, chemical properties, folkloric uses and research studies. Caesalpinia pulcherrima, commonly called peacock flower or barbados pride, is a fastgrowing upright shrub or small tree which typically matures to 10 tall in shrub form or to as much as 20 tall in tree form. Their structures were determined by different spectroscopic methods and ecd calculation.
The recent researches found that patranga caesalpinia sappan shows analgesic, antidiabetic and antibacterial effects. Under natural conditions caesalpinia sappan grows mostly in hilly areas with clayey soil and calcareous rocks at low and medium altitudes. The heartwood of cs has long been used in thai folk medicine to treat tuberculosis. Caesalpinia sappan is a traditional medicinal plant cultivated in india, mayanmar, vietnam.
Wu sq1, otero m, unger fm, goldring mb, phrutivorapongkul a, chiari c, kolb a, viernstein h, toegel s. In this work galactomannan, a biocompatible polymer was isolated from a novel plant source. Caesalpinia sappan, galactomannan, sustained drug release, rheology, thixotropy, gum, herbal formulation. Sappanwood caesalpinia sappan extract gel do not heal. Sapan, caesalpinia sappan, sappan wood, su fang mu. Medicinally the brazilin and volatile oil, extracted from heartwood of sappan tree, can kill bacteria, reduce swelling, and relieve pain. Sappan wood paper names in asia and particularly in china, korea and japan, the papers are intended for a wide range of use.
The wood of caesalpinia sappan is the wooddye that is known to have been used at a large, international scale throughout world history. The plants are trees, shrubs, or, less commonly, lianas. Antiinflammatory activity of an ethanolic caesalpinia. Sapan caesalpinia sappan sappan wood, bukkkum wood. Previous phytochemical investigations indicated that this genus contains an abundant source of cassane diterpenes with different structure types, and most of them showed in vitro or in vivo pharmacological impacts such as. Toxicological studies of caesalpinia sappan wood derived dye. Germplasm resources information network grin online database.
Brazilin, isolated from the heartwood of caesalpinia sappan l, has been. Sappan wood, also known as caesalpinia sappan in scientific name or su mu in pinyin, is a medicinal and dye yielding plant. Higher extraction yield of cs wood was achieved with 95% ethanol for 2 h. Phytochemical and pharmacological aspects of caesalpinia sappan. The ethanolic extract of caesalpinia sappan heartwood. There are more than 100 species, distributed in the tropics and subtropics of both hemispheres. Based on their folkloric use, these plants are expected to be promising candidates for promoting hair growth and preventing hair loss. Common names in english include sappanwood and indian redwood. Antimalarial and antiproliferative cassane diterpenes of. Antiinflammatory activity of an ethanolic caesalpinia sappan extract in human chondrocytes and macrophages. Phenolic compounds from caesalpinia sappan heartwood and. You will be redirected to the full text document in the repository in a few seconds, if not click here. Inula helenium ih is known to possess antifungal, antibacterial, antihelminthic, and antiproliferation activities. Caesalpinioideae sappanwood, bukkumwood, gango origin.
Wo2007066928a1 use of the extract of caesalpinia sappan. Hundreds of tonnes were exported annually to the islamic and mediterranean worlds and europe from the middle ages onwards. Leaves stipulate, bipinnate, alternate, 2045 cm long, 1020 cm. Pharmacognostic studies on sappan caesalpinia sappan linn. It is used in various diseases related to mouth, menorrhagia and other menstrual problems, burning sensantion and skin diseases. Pdf analisa senyawa aktif ekstrak kayu secang caesalpinia. Serial antibacterial furanoditerpenes caesanines ad 14, possessing a cassanetype diterpenoid skeleton with an unusual n bridge between c19c20, were identified from a chinese herb caesalpinia sappan linn. Caesalpinia sappan, biancaea sappan, sappanwood, bukkumwood. In addition, caesanine d 4 showed the first class of dicassane diterpenoid ethers. Caesalpinia sappan or known as secang in indonesia is a flowering tree from leguminosae family which widedistributed throughout southeast asia.
Philippine herbal mediciines an illustrated compilation by dr. Caesalpinia sappan is a traditional medicinal plant cultivated in india, mayanmar, vietnam, sri lanka, and the malay peninsula, and is distributed domestically in china, fujia and taiwan. Galactomannan isolated from caesalpinia sappan l seed can be used as an excellent pharmaceutical excipient for the formulation of matrix tablets. P seed rate and pretreatment about 600800 g seeds may be needed for raising seedlings for planting on 1 hectare of land. Papers for calligraphy and art, papers for ceremonies, paper as a medium of exchange, money paper, papers for making clothes, wall hangings and bedding, papers for architecture, interior design, papers for crafts of. Sapan caesalpinia sappan sappan wood, bukkkum wood, su. Nov 18, 2011 antiinflammatory activity of an ethanolic caesalpinia sappan extract in human chondrocytes and macrophages. The heartwood of the plant is commonly used for the extraction of red dye. Names of sappan wood in various languages of the world are also given. Caesalpinia sappan has been a part of traditional chinese herbal medicine and is widely used in the treatment of dysmenorrheal, blood stagnation, and tetanus. Hahnemannian proving of caesalpinia sappan homeopathy.
Caesalpinia sappan a medicinal and dye yielding plant. Pdf brazilin from caesalpinia sappan wood as an antiacne. Cross sectional microscopic viewstem list of tables 1. International journal of pharmaceuticals and available. Tumbuhan herbal kaya antioksidan ramdana sari dan suhartati balai litbang lingkungan hidup dan kehutanan makassar jl. Pdf caesalpinia sappan an economic medicinal tree for.
Antiinflammatory activity of an ethanolic caesalpinia sappan. In chinese it is called su mu, its other common names are sappan, patang, brazilwood, or sappanwood2, 3. The present work attempts to summarize the pharmacognostical characters of the heartwood of this plant. Sappan wood herb uses, benefits, cures, side effects, nutrients. Analisa senyawa aktif ekstrak kayu secang caesalpinia sappan l. Uses, benefits, cures, side effects, nutrients in sappan wood. Phytochemical and pharmacological aspects of caesalpinia. Historically, membership within the genus has been highly variable, with different publications including anywhere from 70 to 165 species, depending largely on the inclusion or exclusion of species alternately listed under genera such as hoffmannseggia. The ethanol extract dose of 100mgkg and 200mgkg was. They were also tested for their effects on wound healing using fibroblast l929 cells. Caesanines ad, new cassane diterpenes with unprecedented n. Biancaea sappan is a species of flowering tree in the legume family, fabaceae, that is native to tropical asia. Any variations in pre and post proving findings by comparing pre trial and post trial medical examination report forms were also recorded.
Brazilin from caesalpinia sappan heartwood and its. Ash and extractive values, phytochemical tests, hptlc and fluorescence analysis were carried out. Extract of the dried heartwood of caesalpinia sappan l. Toxicological studies of caesalpinia sappan wood derived dye in. The leaves are twice pinnate, and the flowers are fiveparted and in racemes or panicles. Caesalpiniaceae species are being used traditionally and have a wide variety of medicinal properties. Apr 24, 2020 introduction of patranga caesalpinia sappan. The seedlings are ready for planting in the main field during junejuly.